Monday, November 14, 2011

How can we retrieve a solute accidently adsorbed on silica while doing the column chromatography?

I tried to prepare one inorganic complex, but didnt get the product precipated. uming the expected product to be in the solution, along with the unreacted reactants, I decided to separate them by column chromatography. But contrary to my expectation, when i added the reaction mixture dissolved in the eluting solvent to the column, it immediately got adsorbed on the silica, without coming out eluted. So now I have a dry portion of the column with my compound, a light green powder, actually a solid mixture of silica and my desired compound. Could you please help me to retrieve my compound from silica ?

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